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Progress Report: 3rd Gen Oligonucleotide Targeting DUX4 in Mouse Model

Yi-Wen Chen DMV PhD provides an update on investigating 3rd generation oligonucleotides.
by Yi-Wen Chen See grant: Investigation of a third generation oligonucleotide targeting DUX4 using a new mouse model of FSHD Updated 14-Feb-2018 (added more comprehensive informat…

Progress Report: Xenograft Mouse Model

Dr. Bloch provides a brief update of his progress on a xenograft mouse model.
by Robert J Bloch PhD See grant: A Xenograft Model of FSHD for Testing Therapeutics We have been making good progress in our development of methods to generate pure, functiona…

Progress Report: FSHD myofibers cultured from human xenografts

Dr. Robert Bloch provides an update on his research into xenografting.
by Robert J Bloch PhD See grant: FSHD myofibers cultured from human xenografts Our research is devoted to creating mice that have human skeletal muscles, and then using them to…

Walking through Dr. Michael Kyba’s latest mouse model of FSHD

An in-depth analysis of the latest publication on a mouse model for FSHD. What does it mean? Why do we need a mouse model?
In 2008 and 2009, Friends of FSH Research awarded Dr. Michael Kyba a $100,000 grant to begin developing a mouse model for FSHD focusing on the gene, DUX4. It is important to note …