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BETi Compounds Alter DUX4 Expression

Amy Campbell and Fran Sverdrup have recently published a paper on initial results of a screen for compounds that inhibit DUX4 expression.
The recent paper from Amy Campbell and Fran Sverdrup (see also our Ask the Expert article wherein Fran discusses his work on BET inhibitors) provides details on BETi compounds tha…

Potential use of BET inhibitors for FSHD

Q&A by Fran Sverdrup, a Research Fellow at Center for World Health and Medicine.
What are BET inhibitors?  BET inhibitors are a class of drugs with anti-inflammatory and anti-cancer properties. Although no BET inhibitors are yet approved for use in the US or i…