friends of FSH Research

Funding Research for
FSH Muscular Dystrophy Dots

Research Project Grant History

In reverse chronological order

Investigation of a third generation oligonucleotide targeting DUX4 using a new mouse model of FSHD

Yi-Wen Chen DMV PhD
May 28, 2017 to May 28, 2018
Total amount: $78,798

Histochemical and morphometric analysis of FSHD biceps

Kathryn R Wagner MD PhD
Oct 25, 2016 to Oct 24, 2017
Total amount: $77,604

A cell culture model of innate immunity for FSHD

Charles P Emerson Jr. PhD
Oct 23, 2016 to Oct 23, 2017
Total amount: $32,090

Clinical Study using MRI to measure immune response

Leo H Wang MD PhD
Oct 10, 2016 to Oct 09, 2017
Total amount: $52,765

Travel Grant

Hugh JS Dawkins
Aug 31, 2016 to Aug 31, 2016
Total amount: $4,500

Optimizing the Utility of the National Registry for FSHD Research and Trial Recruitment

Rabi Tawil MD
May 12, 2016 to May 12, 2019
Total amount: $34,832

Quantitative Muscle Assessment System

Leo H Wang MD PhD
May 12, 2016 to May 12, 2016
Total amount: $16,500

Structural studies of DUX4-DNA interaction

Hideki Aihara PhD
Mar 01, 2016 to Sep 13, 2017
Total amount: $65,401

Linking genotype to phenotype in human FSHD muscle biopsies and mouse muscle expressing DUX4 protein

Joel R Chamberlain PhD
Nov 01, 2015 to Oct 31, 2016
Total amount: $57,377

FSHD-Research in the Classroom Curriculum

Robert M Kao PhD
Sep 01, 2015 to Aug 31, 2016
Total amount: $4,000

Validation of a PPMO morpholino lead compound in an animal model of FSHD

Scott Q Harper PhD
Jun 01, 2015 to May 30, 2016
Total amount: $50,000

RNA-mediated Epigenetic Silencing of D4Z4 repeats: Implications for targeted therapy for FSHD

Jong-Won Lim PhD
Jul 01, 2015 to Jun 30, 2016
Total amount: $60,180

Investigation of DUX4 activity during development of hESC-derived skeletal muscle

Uli Schmidt PhD
May 01, 2015 to Apr 30, 2016
Total amount: $50,000

FSHD myofibers cultured from human xenografts

Robert J Bloch PhD
May 01, 2015 to Apr 30, 2017
Total amount: $100,000

Optimizing expansion of human muscle stem cells for transplant into mice

Maura H Parker PhD
Jan 01, 2015 to Jun 30, 2017
Total amount: $100,000

Crystallization of DUX4 for Structure Analysis

Hideki Aihara PhD
Jan 01, 2015 to Jun 30, 2015
Total amount: $33,397

Testing Molecular Antagonists of DUX4 3' End Formation

Eric J Wagner PhD
Jan 01, 2015 to Dec 31, 2016
Total amount: $100,000

Cyclic peptides inhibitors of DUX4

Michael Kyba PhD
Jun 01, 2014 to Jun 01, 2015
Total amount: $50,000

Identification of Serum Biomarkers for Measurement of FSHD Progression

Daniel G Miller MD PhD
Jun 01, 2014 to Jun 02, 2016
Total amount: $88,966

In-situ Muscle Test System FLEX Grant

Silvère M van der Maarel PhD
Apr 10, 2014 to Apr 10, 2014
Total amount: $7,500

Generating FSHD‐affected human muscle in mice for testing therapeutic strategies

Maura H Parker PhD
Dec 01, 2013 to Dec 01, 2014
Total amount: $39,930

Screening Chromatin Modifying Genes

Daniel G Miller MD PhD
Aug 16, 2013 to Aug 15, 2014
Total amount: $42,160

Identification of small RNAs generated from the D4Z4 Array

Galina N Filippova PhD
Aug 09, 2013 to Aug 09, 2014
Total amount: $30,000

Identification of Chromatin Modifier Genes Important for DUX4 Silencing

Daniel G Miller MD PhD
Aug 09, 2013 to Aug 09, 2014
Total amount: $50,000

Targeting epigenetic silencing of the 4qD4Z4 repeat array in FSHD

Jong-Won Lim PhD
Jul 01, 2013 to Jul 01, 2015
Total amount: $100,000

Researcher Presentation Support


Jun 08, 2013 to Jun 07, 2014
Total amount: $1,188

Preventing DUX4 Activation and Apoptosis in FSHD Myotubes

Gregory J Block MSc PhD
Feb 20, 2013 to Feb 20, 2015
Total amount: $84,453

Modulators of Epigenetic Disease

Stephen Tapscott MD PhD
Nov 25, 2011 to Nov 25, 2015
Total amount: $500,000

Longitudinal Progression of Edema and Fatty Replacement of Lower Extremity Muscles in FSHD

Seth D Friedman PhD
Nov 18, 2011 to Nov 18, 2012
Total amount: $36,000

Development of anti-DUX4 therapeutics for FSHD

Michael Kyba PhD
Oct 21, 2011 to Oct 21, 2013
Total amount: $25,000

Postnatal modeling of FSHD in mice

Joel R Chamberlain PhD
Sep 01, 2011 to Sep 01, 2013
Total amount: $145,000

Platform development and candidate drug screening for FSHD

Daniel G Miller MD PhD
Aug 18, 2011 to Aug 18, 2013
Total amount: $121,500

Mechanism of Wnt Signaling in Facioscapulohumeral Muscular Dystrophy

Gregory J Block MSc PhD
Apr 15, 2011 to Apr 15, 2013
Total amount: $100,000

Using model organisms to identify new therapies and understand the pathogenesis of Facioscapulohumeral Muscular Dystrophy

Barbara D Page PhD
Nov 01, 2010 to Oct 31, 2012
Total amount: $100,000

RNA Interference as an investigative & therapeutic tool for FSHD

Joel R Chamberlain PhD
Apr 06, 2010 to Apr 06, 2012
Total amount: $100,000

Finalizing a unifying model of FSHD: genetic, transcriptional, and developmental aspects

Stephen Tapscott MD PhD
Sep 15, 2009 to Jan 31, 2010
Total amount: $150,000

MR Evaluation of Skeletal Muscles

Seth D Friedman PhD
Aug 15, 2008 to Sep 14, 2009
Total amount: $15,690

DUX4 and D4Z4 RNA and protein production as candidates for FSHD

Stephen Tapscott MD PhD
Aug 15, 2008 to Aug 15, 2010
Total amount: $100,000

D4Z4/DUX4 Induced Pathologies in Mice

Michael Kyba PhD
Aug 01, 2008 to Aug 01, 2010
Total amount: $100,000

Analysis of allele-specific RNA transcription in FSHD

Sara T Winokur PhD
May 29, 2008 to May 28, 2009
Total amount: $28,000

Development of an RNAi-based therapy for FSHD

Joel R Chamberlain PhD
Jul 09, 2007 to Sep 01, 2009
Total amount: $100,000

DUX4 expression in FSHD skeletal muscle

Alexandra Belayew PhD
Jun 28, 2007 to Jun 28, 2008
Total amount: $14,845

FSH Research Seattle Conference


Dec 01, 2006 to Dec 01, 2006
Total amount: $2,517

FSHD Related Defects in Human Myogenesis

Daniel G Miller MD PhD
Jun 14, 2006 to Sep 14, 2008
Total amount: $100,000

Effects of FRG1 on muscle behavior

Brian K Kennedy PhD
Oct 01, 2005 to Sep 30, 2008
Total amount: $150,000

Total funding to date: $3,300,193